Founded by Greeks in the pre-Christian era, the Catalan town is set on a lovely curve of beaches on Spain’s Costa Brava. It is crowned by the Castell de la Trinitat, which anchored the wall that encircled the entire town in medieval times. It was the site, until 2011, of Ferran Adria’s Michelin three-star restaurant El Bulli, which will reportedly reopen in 2014 as a culinary creativity center. Shop for a souvenir from the back of a street hawker’s donkey, or wander to nearby Figueres or Cadaques to visit one of Salvador Dali’s museums.

Settled first by the Romans, then ruled by Genoans for nearly half a millennium, Calvi was freed by Corsica‘s native son Napoleon in 1791. In 1982 it was given special status and now enjoys a uniquely autonomous position within the realm of France. Ringed with alternating precipitous cliffs and fine sand beaches, the island resembles a mountain thrust up out of the water, but its ruggedness is tempered by brilliant sunlight and groves of olive and orange trees. Napoleon once said that he could recognize Corsica with his eyes closed – by its perfume alone. While touring Corsica, be advised that the roads about this mountainous island are quite winding with many curves.

The Madeira Archipelago, consisting of the islands Madeira, Porto Santo and Desertas, is situated in the Atlantic, about 400 miles from the African coast and 560 miles from Lisbon. Discovered by the Portuguese in 1419, Madeira, the largest of the islands, became of great importance to Portugal for its sugar production and later on for the cultivation of wine. The unusually temperate oceanic climate and extraordinary scenery had Northern Europeans flocking to Madeira as early as the 18th century to spend the winter months. The winning combination of high, rocky peaks, steep green ravines and waterfalls in the interior, with the flowering charm of Funchal still attracts nearly half a million visitors each year.

Originally built by Emperor Trajan who had a villa here, Civitavecchia has flourished as a major port for Rome since the 13th century. Today it is an important ferry terminal and for many travelers the gateway to the Eternal City, Rome. The Renaissance fortifications that surround the harbor area were begun by Bramante and completed by Michelangelo in 1535.

This harbor on the eastern shore of Sicily near Messina gives us close access to the fabulous Greco-Roman ruins of Taormina, as well as the active volcano Mt. Etna. The temples, streets and large amphitheater of Taormina make it one of Italy’s premier ancient sites. Its location overlooking the sea and with the backdrop of snow-capped Etna complete the package and make it among the most famous attractions in the Mediterranean region. Giardini Naxos itself boasts a lovely beach at Lido Europa, and intrepid visitors can climb Mt. Etna to see a volcano close up

One of the best preserved medieval towns of the Adriatic, Kotor is protected by UNESCO. Between 1420 and 1797, the area was under the rule of the Republic of Venice and the Venetian influence can be seen in its architecture. The Gulf of Kotor is sometimes called the southernmost fjord in Europe, although it is actually a submerged river canyon. The overhanging limestone cliffs of Orjen and Lovcen complete one of the Mediterranean‘s most beautiful landscapes.

Located in central Dalmatia Zadar is one of the Adriatic‘s most historically interesting towns with a wealth of sightseeing and exciting nightlife. Zadar was founded by the Romans, attacked by the Turks, ruled by the Austrians and made part of Italy until 1943 when the Germans moved in. Allied bombing destroyed much of the historic centre which was rebuilt after the war only to suffer more attacks by Yugoslav forces in 1991. In recent years Zadar has undergone a startling revival. Cafes and bars are filled, museums and churches have been restored and tourists pour in to take boats to nearby islands.

Located on the tip of Istria, Slovenia‘s main port was an island until the 19th century, but local history goes back much further. Called Aegida by the Greeks, Capris by the Romans and Justinopolis in Byzantine times, Koper was the influential city in the Venetian Empire and five mayors sat on the throne of the Venetian doges. Today monuments of this Golden Age line the cobblestone streets of an Old Town that boasts a wealth of architecture, cultural monuments and intriguing shops.

Vodice is a popular seaside town on the Dalmatian coast of the Adriatic Sea. It has the familiar red-tiled roofs and wide stone seaside promenades of other Dalmatian ports. In the town, there are several interesting features. One is the old Church of St. Cross dating from 1402, and the newer, baroque Parish Church of St. Cross from 1746, with a tall bell tower. The Church of St. Elijah is even older, dating from 1298. There are several popular pebble and sand beaches around Vodice. Outside town are a pair of fields with archaeological remains of Roman era occupation, including walls, cisterns, wells and fortifications. Each field also holds a small church. The Coric Tower is a fortified manor built by a powerful family during the mid-17th century to protect against Turkish attacks. From Vodice it is also easy to access the seaside town of Sibenik, the waterfalls and pools of Krka National Park and the offshore islands of the Kornati National Park.

One of the best preserved medieval towns of the Adriatic, Kotor is protected by UNESCO. Between 1420 and 1797, the area was under the rule of the Republic of Venice and the Venetian influence can be seen in its architecture. The Gulf of Kotor is sometimes called the southernmost fjord in Europe, although it is actually a submerged river canyon. The overhanging limestone cliffs of Orjen and Lovcen complete one of the Mediterranean‘s most beautiful landscapes.

Pylos occupies a superb and dominant position on one of the best natural harbors in Greece. Your gaze is inevitably drawn to the bay that is almost landlocked due to the position of the offshore island of Sfaktira. The Battle of Navarino, which took place here one night in 1827, effectively sealed Greek independence. An unusually stylish town with a pair of medieval castles, Pylos is an excellent base for exploring the Peloponnese. Enjoy time at leisure to explore this town, which spreads across the slopes of the hill, its picturesque cobbled lanes lined with two-story houses. Opposite the harbor, in the Square of the Three Admirals, a three-sided column rises between two canons – one Turkish and the other Venetian. The figures of the admirals of the three fleets, English, French and Russian that defeated the Turko-Egyptian navy in the Battle of Navarino are represented. A visit to Niokastro, one of the two castles guarding the harbor, affords wonderful views out over the bay.

Held to be one of the loveliest small towns in all the islands, Navplion has a tradition and culture all its own. The sheltered location, below a rocky headland crowned by a Venetian fortress is perhaps unrivaled in Greece. After the Greek revolution of the early 19th century, Navplion served as the first modern capital. The neoclassical houses, large official buildings and carefully planned seafront streets all date from this period.

Piraeus has been the port for Athens since 482 BC. The busy harbor is filled with ferries and cruise ships making their way to the Greek Islands and other Mediterranean cities. The busy metropolis of Athens and its treasure trove of antiquities lie just a few miles from the port. Even as the reality of the modern city took hold, with its high-rise apartments, crowded sidewalks and bustling traffic, the beauty of the Acropolis, the outstanding museums, charming cafés, sidewalk markets and startling views come together in a cultural mosaic for all to enjoy.

Monemvasia was once on the Peloponnese mainland. Then an earthquake turned it into an island. It is now joined to the mainland by a narrow causeway that limits access, originally for reasons of defense. The tall, flat isle is completely honeycombed with nooks and grottoes, narrow alleys and rock-carved rooms. Clearly it was a formidable redoubt in times of attack, and earned its nickname the Gibraltar of the East. The upper town, long uninhabited, has narrow pathways leading to the Byzantine Aghia Sophia church, and remains of the medieval fortress and walls. In the lower town, look for the bell tower that leads you to Elkomenos Square, with its namesake medieval Elkomenos Christos church and a small museum.

This charming village of white houses climbing up the slopes is beautifully situated on the sparkling Gulf of Mirabello. The attractive Venetian harbor is surrounded by restaurants, outdoor cafes and clusters of shops selling everything from necessities to souvenirs. The ship docks in the center of town, and you are able to wander at will and enjoy the atmosphere of Crete‘s foremost resort.

The quintessential Greek island of Mykonos is marked by whitewashed houses, domed churches, imposing windmills, and a labyrinth of winding streets designed to disorient pirates. Everywhere there is a dash of bright, bold blue – doors, shutters and window frames, sea and sky. The harbor bustles with colorful fishing boats, vendors selling fish and locals gathered with visitors in the casual seaside cafes. The port even comes with two beloved mascots, the pelicans Petros and Irini.

A popular holiday and resort destination, Cesme is located on a promontory on the tip of a peninsula that carries the same name. The town itself is dominated by the medieval Cesme Castle, while the back streets invite a casual stroll with their old Ottoman and Greek houses that charm passers-by. South of the castle there is an Ottoman caravanserai built in 1528 that has since been transformed into a lovely boutique hotel, and check the Greek Orthodox church of Ayios Haralambos to see the current art exhibition. Along with the historical attractions, visitors will enjoy local pleasures, such as a dip in the thermal baths followed by the culinary delights of native fruits, artisan cheeses and local wines.

Kusadasi, which means “bird island,” is set in a superb gulf known for its sparkling water, broad sandy beaches and large marina. The city has managed to retain a certain earthiness while doing a brisk trade in Turkish carpets and leather goods to visitors. The town‘s old quarter is a picturesque maze of winding streets and houses adorned with flowers and birdcages. In the center stands a 17th-century caravanserai, now converted into a hotel. The resort is also gateway to important sites of archaeological and religious interest.

Spanning Europe and Asia, exotic Istanbul is one of the world‘s most fascinating cities. Domes and minarets enhance the skyline. In the old Stamboul area, traces remain of every city built since the community was established over 600 years before Christ. Once Rome‘s eastern capital, Istanbul was also the center of the huge Ottoman Empire. Landmarks include Hagia Sophia, once Christendom‘s greatest church; the Blue Mosque with its striking Iznik tiles; Topkapi Palace, containing a sultan‘s ransom of treasures; Chora Church with its Byzantine mosaics; and the Grand Bazaar, the ultimate shopping experience.

Between 1865 and 1866, English explorer Frank Calvert and German archaeologist Heinrich Schliemann began digging trenches through a hillock outside Canakkale and discovered layer upon layer of ancient cities. Ultimately nine cities that had thrived and fallen atop each other were identified with the legendary Greek city of Troy. The site is a UNESCO World Heritage Site.

Deserted for centuries because of constant raids by pirates and the Turks, this tiny arid island was first settled in 1088 when the Emperor of Constantinople made it a gift to the monk Christodoulos Latrnos so that he could establish a monastery in honor of St. John the Divine on the site. Patmos has been a place of scholarship and religious enlightenment ever since. Today this modern pilgrimage site is a quiet respite from the tourist havens many other Greek isles have become.

Best known of the Dodecanese Islands, Rhodes is a fascinating architectural patchwork of her past. Here the legacy of the ancient Greeks mingles with that of besieging Turks, crusading knights, and occupying Italians. Twin bronze deer, the symbol of Rhodes, guard the Mandraki Harbor where the 100-foot Colossus is said to have stood, a wonder of the ancient world. The medieval Crusader City is dominated by the Palace of the Grand Masters, while cobbled streets lead to the bustling bazaar and a lively harbor that is a center of the international yachting scene.

“Thira, the Wild Island” and “Kalliste, the Fairest One” – all terms of endearment for this seductive, volcanic Greek island in the Sea of Crete. Extraordinary for its black sand beaches and sheer limestone cliffs, Santorini also showcases remnants of the Phoenician, Spartan and Minoan cultures, which fell under the island‘s spell – an unvarying, irresistible lure that continues to this day. Fira, the picturesque, pedestrian-only capital, is reached from the seaport via a short cable car ride that offers thrilling views as you ascend.

Piraeus has been the port for Athens since 482 BC. The busy harbor is filled with ferries and cruise ships making their way to the Greek Islands and other Mediterranean cities. The busy metropolis of Athens and its treasure trove of antiquities lie just a few miles from the port. Even as the reality of the modern city took hold, with its high-rise apartments, crowded sidewalks and bustling traffic, the beauty of the Acropolis, the outstanding museums, charming cafés, sidewalk markets and startling views come together in a cultural mosaic for all to enjoy.